The claim came as Odom continued to fight for his life after being found unresponsive at the Love Ranch in Crystal, Nevada, on Tuesday afternoon.
According to police, the caller told the 911 operator Odom had used cocaine on Saturday, but it was unclear if the use had continued into the weekend. The person also reported that Odom had taken up to 10 tabs of a sexual enhancement drug over the past three days. It was not clear which specific drug the caller was referring to.
Officials from the Nye County Sheriff's Office said that his blood had been taken by investigators and was being processed.
Odom's estranged wife, Khloe Kardashian, remains by his bedside at a hospital in Las Vegas.
'BIG BANG' CO-STARS SQUASH DATING RUMORS: Kaley Cuoco and her Big Bang Theory co-star Johnny Galecki shut down rumors they're dating again in the wake of her recent split with husband Ryan Sweeting.
Cuoco posted a pic of her and Galecki on Instagram bumping fists and captioned it, "So sorry to disappoint , but no home wreckers or secret flings going on here. Me and johnny galecki are just the best of buds," adding, "Leonard and Penny will just have to suffice!!!" -- a reference to the characters they play on TV.
The two dated for almost two years before splitting in 2010.
The same day, Gilecki posted a slightly different photo with a similar sentiment: "No scandals / home wreckers / pregnancies here, y'all. Just profound friendship." [PHOTO]
Cuoco and Sweeting got engaged in September 2013, and tied the knot that New Year's Eve. They announced their breakup in September. Galecki split from actress Kelli Garner in August after more than two years together.